Alefacept (Amevive ®) is a recombinant, fully human fusion protein that selectively targets memory T cells that have been implicated in the pathogenesis of psoriasis. Alefacept is approved in the ...

Alefacept is a genetically modified immunosuppressive drug prescribed for treating moderate to severe chronic plaque psoriasis in adult patients who are candidates for phototherapy or systemic therapy ...

Learn the correct pronunciation of the Alefacept, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings ...

Individuals with new-onset type 1 diabetes who took two courses of alefacept (Amevive®, Astellas Pharma Inc.) soon after diagnosis show preserved beta cell function after two years compared to those ...

Patients were eligible for inclusion if they developed extensive cGVHD that was resistant to at least two lines of therapy, which in all patients included prednisone (⩾1 mg/kg), and the minimum ...

Alefacept (Amevive) is a novel dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leucocyte function antigen-3 (LFA-3) linked to the Fc portion of human IgG1 ...

The psoriasis drug alefacept has met a number of targets in a phase 2 trial to discover whether it can prolong and improve insulin production in newly diagnosed patients with type 1 diabetes. The ...

CHICAGO – Patients with psoriasis treated with the drug alefacept experienced a reduction in severity of their skin disease, according to an article in the December issue of The Archives of ...

Standards of Medical Care in Diabetes Released for 2013 Alefacept could be useful to preserve β-cell function in patients with new-onset type 1 diabetes. Mark R. Rigby, MD, from the Indiana University ...

As demonstrated in clinical trials, alefacept is well tolerated after both IV and IM administration. Adverse events were generally mild, and discontinuation rates due to adverse events were low and ...

Individuals with new-onset type 1 diabetes who took two courses of alefacept (Amevive®, Astellas Pharma Inc.) soon after diagnosis show preserved beta cell function after two years compared to those ...