Benzylisoquinoline alkaloids (BIAs) represent a diverse group of plant secondary metabolites that are of profound pharmacological importance. These compounds, which include opiates, antimicrobial ...

Catharanthus roseus, commonly known as Madagascar periwinkle, is celebrated for its production of monoterpenoid indole alkaloids (MIAs), a diverse group of specialised metabolites with considerable ...

Making chemical handles that latch onto amino acids is a strategy used to make covalent drugs, antibody-drug conjugates, and biochemical probes. Cysteine and lysine are common points of attachment, ...

Tropane alkaloids (TAs) are heterocyclic nitrogenous metabolites found across seven orders of angiosperms, including Malpighiales (Erythroxylaceae) and Solanales (Solanaceae). Despite the ...

Plants make substances called alkaloids to protect themselves, and humans have long taken advantage of these chemicals, using ...

Using high-fidelity sequencing and chromosome conformation techniques, the researchers constructed a 2.63 Gb genome for H. cordata, resolving its decaploid nature (2n = 10x = 90). Analysis revealed ...

A research team presents an overview of recent advances in the microbial biosynthesis of L-tryptophan (L-Trp) and its ...

Plants in the genus Tripterygium, historically utilized in traditional medicine and agriculture across East Asia, have been applied for pest control as well as for curing diseases such as rheumatoid ...

This review synthesizes progress in pathway optimization, regulatory rewiring, and microbial cell factory design that has ...