Advances in organ and computer models are raising the prospect that some animal experiments could be eliminated. But there ...

Due to advancements in genetic engineering, small animal models are continuing to change in response to market needs. Model developers strive to better reflect the role of this important asset in both ...

LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...

Ace Therapeutics announced custom animal models of hypertension, designed to help understand hypertension pathogenesis ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

Periodontal disease, represented by periodontitis, is the leading cause of tooth loss and affects close to one in five adults worldwide. In most cases, this condition occurs as a result of an ...

Sarcoidosis is an inflammatory disease in which immune cells form tissue nodules in various organs, which can drastically impair organ function. Now a MedUni Vienna research team led by Thomas ...

Suggested Citation: "1 Introduction to Precision Medicine and Animal Models." National Academies of Sciences, Engineering, and Medicine. 2018. Advancing Disease Modeling in Animal-Based Research in ...

Visit NAP.edu/10766 to get more information about this book, to buy it in print, or to download it as a free PDF. 1 As discussed in Chapter 2, current animal models do not adequately reflect the human ...