LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...

Suggested Citation: "1 Introduction to Precision Medicine and Animal Models." National Academies of Sciences, Engineering, and Medicine. 2018. Advancing Disease Modeling in Animal-Based Research in ...

Every year, more than 100 million animals are used globally in biomedical research, yet over 90% of drugs that appear effective in animal trials fail during human clinical testing. 1 This staggering ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery. Despite billions of dollars ...

A recent op-ed in The Hill praising the National Institutes of Health’s new initiative to promote human-based technologies as a “major victory for animal ethics in science” oversimplifies a far more ...

K. C. Kent Lloyd is a professor in the Department of Surgery, School of Medicine, director of the Mouse Biology Program and NAMs Testing Center and associate director of the Comprehensive Cancer ...

Washington, DC—Last month, both the National Institutes of Health and the US Food and Drug Administration announced plans to phase out the use of animals in scientific research. The Animal Welfare ...

Last November, the UK government announced a bold plan to phase out animal testing in some areas of research. Animal tests for skin irritation are scheduled for elimination this year, and some studies ...