Astrocytes are integral constituents of the central nervous system, serving roles that extend far beyond mere structural support. These specialised glial cells are crucial for maintaining homeostasis, ...

Silent cells deep in your spinal cord may hold a surprising key to healing after devastating injuries and brain disease. A ...

Yunseon Yang, Jae-Jin Song, Yu Ree Choi, Seong-hoon Kim, Min-Jong Seoka, Noviana Wulansari, Wahyu Handoko Wibowo Darsono, Oh-Chan Kwon, Mi-Yoon Chang, Sang Myun Park, Sang-Hun Lee Proceedings of the ...

Epilepsy, where patients suffer from unexpected seizures, affects roughly 1% of the population. These seizures often involve repetitive and excessive neuronal firing, with the trigger behind this ...

Astrocyte activity precedes the onset of epileptic neuronal hyperactivity episodes. (A) With cytosolic calcium ion increase, excitatory actions from astrocytes to neurons are likely to be initiated.

The potential effects of astrocyte dysfunction in neurodegenerative diseases are summarized in Figure 2. AD is characterized clinically by cognitive loss in two or more domains, including memory, ...

When epileptic patients suffer seizures, their brain is undergoing repetitive and excessive neuronal firing. But what triggers this has stumped scientists for years. Now, researchers have used ...

The mechanism of astrocytic autophagy plasticity plays a crucial role in AD. When the autophagy-regulating genes (LC3B and SQSTM1) in astrocytes are activated, Aβ is efficiently removed, which is ...

Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the brains of mouse models of Alzheimer’s disease and preserves cognitive function ...

Young minds are easily molded. Each new experience rewires a child’s brain circuitry, adding and removing synaptic connections between neurons. These wiring patterns become more stable with age, but ...

A study by researchers at Baylor College of Medicine may change the way we understand memory. Until now, memories have been explained by the activity of neurons that respond to learning events and ...