Researchers at Duke University have shown that blocking an enzyme involved in iron regulation not only kills multiple myeloma cancer cells, but also increases the effectiveness of current therapies ...

Hearing loss is a common and often permanent side effect of cisplatin, a widely used chemotherapy drug for many solid tumors. Cisplatin accumulates in the inner ear, where it damages sensory hair ...

Two enzymes from the protein disulphide isomerase (PDI) family enable prostate cancer cells to grow, survive, and resist treatment. This discovery, however, could be taken as an advantage to improve ...

The emergence of cancer drug resistance remains one of the most pressing problems in cancer care and there is a critical need to devise approaches to mitigate it. However, the molecular mechanisms ...

Scientists based in Australia and China have identified a pair of pesky enzymes responsible for prolonging prostate cancer – which means we can potentially target them for quicker and more effective ...