An analysis of two large cohort studies finds that carriers of disease-causing variants within genes for three ...

Medically reviewed by Christopher Lee, MD Key Takeaways ATTR-CM often requires a team of healthcare providers, including cardiologists, specialists, and primary care doctors.Caregivers play an ...

Glycogen storage disease (GSD) type III (OMIM 232400) is due to glycogen debranching enzyme (GDE; EC 3.2.1.33) deficiency encoded by the AGL gene. The estimated incidence of the disease is estimated ...

AFTX-201 uses a proprietary capsid to deliver a human BAG3 transgene, aiming to restore cardiac function with lower doses than conventional gene therapies.

Cardiomyopathy is a disease of the heart muscles which may cause them to become enlarged and inflamed. Inflamed muscles become stretched, weak, less efficient at pumping blood and less able to ...

Please provide your email address to receive an email when new articles are posted on . Genetic risk for dilated cardiomyopathy was tied to elevated risk for secondary cardiomyopathies related to ...

Subtle onset or changes in symptoms of ATTR-CM can indicate worsening heart failure. Learn how to track symptoms and when to seek medical attention.

"Medical Journeys" is a set of clinical resources reviewed by physicians, meant for the medical team as well as the patients they serve. Each episode of this 12-part journey through a disease state ...

Capricor Therapeutics (CAPR) upgraded to Buy as FDA accepts HOPE-3 for Deramiocel in DMD cardiomyopathy; PDUFA Aug 22, 2026. Click here to read more.

Hypertrophic cardiomyopathy (HCM) affects one in 500 people in the general population. In most cases, HCM is caused by genetic mutations. Doctors usually discover HCM during cardiac testing (an ...

MRI results highlighted that patients with baseline cardiomyopathy saw a 3.3 percentage-point improvement in left ventricular ejection fraction. ・Capricor has already submitted a BLA for Deramiocel to ...

In this opening episode titled, ‘Transthyretin Amyloid Cardiomyopathy (ATTR-CM): Clinical Burden and Diagnostic Challenges,’ moderator, Dr. Ryan Haumschild, and panelist, Dr. Kevin Alexander, ...