Antibiotic resistance is racing toward a global crisis, with “superbugs” projected to cause over 10 million deaths annually by 2050. Now, scientists at UC San Diego have unveiled a powerful new CRISPR ...

Bacteria get invaded by viruses called phages. Scientists are studying how bacteria use CRISPR to defend themselves from phages, which will inform new phage-based treatments for bacterial infections ...

Cat1 monomers seen here in shades of pink and purple, while cA4 glueing the dimers to extend the filament are in orange. Every living creature on Earth needs to protect itself from things that would ...

Bacteria combat phage infection using antiphage systems and many systems generate nucleotide-derived second messengers upon infection that activate effector proteins to mediate immunity. Phages ...

Like people, bacteria get invaded by viruses. In bacteria, the viral invaders are called bacteriophages, derived from the Greek word for bacteria-eaters, or in shortened form, "phages." Scientists ...

In nature, the best-known CRISPR system, CRISPR-Cas9, cuts any RNA or DNA it recognizes as foreign, and thereby protects bacteria from viral attacks. Another CRISPR system, one that is relatively ...

Researchers have identified an unusual arabinose-based modification of bacteriophage DNA that helps viruses evade bacterial ...

Phage therapy is an emerging strategy that uses viruses that target bacteria to restore gut balance and treat microbiome-related diseases. Ongoing research and early trials show promise, but ...