在包括乳腺癌、肺癌和黑色素瘤在内的晚期癌症中,脑膜转移疾病(Leptomeningeal Disease, LMD)是一种与神经功能快速恶化相关的疾病,可能发生。治疗选择仍然有限,但研究人员认为中枢神经系统内的免疫细胞是理解该疾病生物学特性和制定治疗策略的关键。为了弥补这一差距,来自西班牙国家基因组分析中心(National Center for Genomic Analysis, CNAG)和法 ...
Cerebrospinal fluid (CSF) leaks represent a significant clinical challenge, marked by the aberrant escape of CSF from its usual confines into adjacent structures such as the paranasal sinuses, which ...
It may be possible to identify the presence of an aggressive brain tumor in children by studying their cerebrospinal fluid, according to new research led by Johns Hopkins Kimmel Cancer Center ...
Exploring the genetic blueprint of cerebrospinal fluid proteins, this study uncovers new markers and therapeutic targets that may unlock advancements in Alzheimer’s diagnosis and care. Study: ...
In a study published in Nature, South Korean researchers led by Director Koh Gou Young of the Center for Vascular Research within the Institute for Basic Science (IBS) have uncovered a distinctive ...
Earlier detection and treatment optimization enabled by CNSide may reduce overall LM-related healthcare costs by ~40% (33%-47%) Potential savings are driven by earlier therapeutic intervention, ...
Phase 1 dose-escalation trial using convection-enhanced delivery of radiolabeled monoclonal antibody for diffuse intrinsic pontine glioma following external radiation therapy. Serial plasma and CSF ...
Using single-cell sequencing, researchers found distinct immune profiles in different CNS tumors, highlighting its potential as a prognostic tool.
IDH mutation status impact on in vivo hypoxia biomarkers expression: New insights from a clinical, nuclear imaging, and immunohistochemical study in 34 patients with glioma. Background: Cerebrospinal ...
SAN DIEGO--(BUSINESS WIRE)--Biocept, Inc. (Nasdaq: BIOC), a leading provider of molecular diagnostic assays, products and services, has announced the full commercial launch of CNSide™, its ...