The activated leukocyte cell adhesion molecule (ALCAM) is a critical member of the immunoglobulin superfamily that mediates both homotypic and heterotypic cell interactions. It plays a central role in ...

AMES, Iowa – Sanjeevi Sivasankar knows a lot about how the healthy cells in your body stick together. He and his research team have studied cell adhesion proteins called cadherins. They’ve developed ...

Cancer remains one of the world’s most serious health threats, especially when it spreads beyond its original site. That ...

Molecularly targeted therapies are increasingly relevant in clinical oncology, as they enable the selective modulation of specific biologic targets—such as enzymes or receptors—by inhibiting or ...

Scientists at Duke-NUS Medical School have identified a molecular "switch" that determines whether pancreatic cancer cells resist chemotherapy or respond to it—a finding that could help convert some ...

Immunotherapy has revolutionized the way physicians treat patients. Previously, chemotherapy was the standard-of-care with the goal to eliminate tumor cells by dysregulating their ability to ...

A groundbreaking study may change how doctors treat glioblastoma, one of the deadliest brain cancers. Researchers Virginia Commonwealth University have developed a powerful new therapy using an ...

A guardian molecule ensures that liver cells do not lose their identity. The discovery is of great interest for cancer medicine because a change of identity of cells has come into focus as a ...

Phase II Trial of Nivolumab Plus Doxorubicin, Vinblastine, Dacarbazine as Frontline Therapy in Older Adults With Hodgkin Lymphoma Colorectal cancer (CRC) remains a major global health burden, being ...

A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor (CAR) T cells kill cancer. Investigators from Baylor College of Medicine, ...