Protocadherins, a subfamily within the cadherin superfamily, are fundamental to the precise organisation of neural circuits. They contribute to cell adhesion mechanisms that underlie synaptic ...
Time-lapse movie of the hub molecule afadin when momentarily released from the cytoskeleton. Quickly, it convenes in droplets, revealing the mechanism it employs to direct cellular attachment to the ...
Leukocyte adhesion deficiency (LAD) represents a group of rare, genetically determined immunodeficiency disorders that impair the ability of white blood cells to adhere to vascular endothelium, ...
New research reveals how a class of neurons that help coordinate communication in the brain link up with their target cells, ...
Cells attach to each other through carefully arranged molecules. A research team has now found that the way they organize to find their proper places is similar to how grease drops self-organize in ...
CytomX is advancing its ADC candidate CX-2051 in the oncological field. CX-2051 shows an impressive response rate and improved progression-free survival in heavily pretreated colorectal cancer ...
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Antibodies Outsmart Germs, Prevent Cell Adhesion
Pathogens can create sticky situations. When microbes invade the body to cause an infection, often one of their first lines of attack is to cling ...
Certain antibodies employ unusual tactics to keep germs from attaching to cells in our bodies. Their defensive strategies ...
Researchers have created a way to guide and control the development of stem cells into specific tissues and organs, opening the door to developing a means of one day tackling complex diseases like ...
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