免疫学界一直致力于通过评估免疫细胞中细胞因子的产生、基因表达和表面标记物的表达来识别和测量免疫反应。这些研究大大拓宽了我们对免疫系统基本结构和功能的理解，揭示了激活免疫细胞产生细胞因子的机制；然而，尽管细胞因子反应细胞在调节炎症反应中起着关键作用，但 ...

Fast, gentle, and highly specific glycoprotein labeling compatible with downstream immunofluorescence, enabled by ...

Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole new way, thanks to a new method involving CRISPR gene-editing technology. The ...

CRISPR gRNA is used to knock out specific genes in cells, which is barcoded into the sEVs they release. By analyzing the barcodes in the sEVs and cells, researchers can better understand the factors ...

A cell’s morphology comprises vast amounts of information on cell health and differentiation state and yields insight into cell phenotype. Biologists utilize this information on a daily basis to aid ...

Movie 1: Movement of single nucleosomes in living human cells. The movie shows nucleosome fluctuations in euchromatin (left), where gene expression is active, and in heterochromatin (right), where ...

A new study in Nature Chemical Biology introduces SNAP-tag2, an enhanced version of the widely used SNAP-tag self-labeling protein (SLP). SNAP-tag2 offers faster protein labeling, improved ...

One of the longstanding challenges in chemical biology has been finding ways to directly observe biological processes at work inside living cells without disturbing the action. In order to unlock new ...

QDs can bind covalently or non-covalently to biomolecules like antibodies, proteins, peptides, aptamer nucleic acids, small molecules, liposomes, lectins, and monosaccharides to identify specific ...