During embryonic stem cell (ESC) development, pluripotent stem cells transition from a naïve state into a primed state before they take their first steps toward a lineage commitment. Jacob Hanna, a ...

Cellular aggregates derived from human stem cells in previous studies could not be considered genuinely accurate human embryo models, because they lacked nearly all the defining hallmarks of a ...

For several years, researchers studied human embryonic stem cells (ESCs) to understand the unique features of these pluripotent cells, but on their own, they poorly resembled the complex structures ...

Around eight days after fertilization, the human embryo implants in the endometrium (the tissue that lines the uterus). After implantation, it enters a developmental phase that is not well understood ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

HeX-Embryoid model showing early blood cells (green) that have formed inside of blood vessels (red) surrounded by yolk sac mesoderm cells (blue) that support these tissues. University of Pittsburgh ...

Scientists have grown a scalable new embryo-like model that unshrouds some mysteries of early human development, including blood cell formation, or hematopoiesis—a first for the field. In an article ...

Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...

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University of Pittsburgh researchers have developed a new embryo-like model derived from adult cells that replicates key features of early human development, including the generation of blood cells.

University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects of very early human development—including the production ...