Cell line development (CLD) follows a process that has only changed slightly since it was established in the early days of biopharmaceutical development. The steps to create a stable, manufacturing ...

With three decades of experience, over 200 client partnerships and several cell-line development platforms, Aragen Bioscience supports its global biopharma clients with end-to-end biologics ...

Most research labs can make cells that produce antibodies. The trick is making those antibodies in sufficient quantity and quality to use throughout clinical trials and for manufacturing scale-up.

Production of recombinant monoclonal antibodies (mAbs) for therapeutic use is a multibillion dollar industry. At present, mammalian cell lines are the workhorses of the biotechnology industry, due to ...

Preventing selection bias in the cell line is a critical aspect of cell line development. Selecting clones based on factors such as stability, antibody secretion, or other metrics can result in a ...