本综述系统阐述了肠道菌群代谢产物氧化三甲胺(TMAO)在心血管、肾脏及代谢性疾病中的核心作用机制。文章聚焦于TMAO从 ...
TMAO作为肠道菌群代谢物在心肌梗死中发挥关键作用,通过激活炎症信号通路、内皮功能障碍及线粒体能量代谢紊乱促进疾病进展,并可作为生物标志物用于风险评估,未来治疗可靶向调节菌群及代谢酶活性。 肠道微生物群与心血管疾病关联性研究:以TMAO为关键 ...
A recent study published in the journal Nutrients investigates how the incidence of diabetes is associated with altered trimethylamine N-oxide (TMAO) levels. Study: Dynamic changes in gut ...
Mentor: D.J. Ferguson, Ph.D. The primary goal of this research is to uncover the enzymes responsible for the breakdown of both carnitine and choline in CJ25. Understanding these metabolic processes ...
ITHACA, N.Y. - In the last five years, some scientists have cautioned against eating eggs and meat because these foods generate a common dietary compound, trimethylamine N-oxide (TMAO), that research ...
An Expert Interview With Stanley L. Hazen, MD, PhD Background to the Interview The Role of Microbes in the Gut and Compounds in Red Meat The Role of TMAO in Cardiovascular Residual Risk References The ...
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