STANHOPE, N.J., June 23, 2025 /PRNewswire/ -- Pilonidal disease—a chronic infectious and inflammatory condition affecting the skin and underlying tissue near the tailbone—is a common disorder ...

Also known as a pilonidal cyst, the condition forms when a sac of tissue fills with air or fluid in the crease of your buttocks. Pilonidal cyst, doctors say, is mostly caused by a skin infection.