本研究揭示了 Cryptococcus neoformans fbp1Δ 疫苗的免疫原性机制，发现胶囊和Cytokine Inducing Glycoprotein 1（Cig1）蛋白共同参与疫苗诱导的Th1免疫应答，Cig1作为Fbp1 E3连接酶的底物，其过表达增强疫苗效果，而Cig1缺失导致保护性免疫减弱，为优化真菌疫苗提供了新靶点。

A lab has completed a six-year study to examine the virulence of 38 clinical isolates from various strains of Cryptococcus. Ultimately, the goal is to find ways to stop deadly disease caused by ...

Dr. Gerry Wright's lab has identified a molecule that could revive an entire class of antifungal drugs and help combat ...

Scientists have uncovered a way to make existing antifungal drugs work again against deadly, drug-resistant fungi. Fungal infections claim millions of lives worldwide each year, and current medical ...

Ultimately, the goal is to find ways to stop deadly disease caused by Cryptococcus neoformans from developing in humans and animals. But until that time, finding new and better ways to treat already ...

Two cannabis-derived compounds have shown remarkable effectiveness against fungal pathogens in laboratory tests, according to new Macquarie University research. In a study published in The Journal of ...