Minor groove binding compounds represent a diverse class of small molecules that interact with the DNA double helix by inserting into its narrower, minor groove. This mode of binding affords a unique ...

Dps proteins (DNA-binding proteins from starved cells) are vital components in the defence strategies of bacteria facing environmental stress. These proteins not only bind and compact chromosomal DNA, ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

A genomic atlas of Nematostella vectensis reveals how primitive animals created multiple cell types millions of years ago, ...

Research into transcription factors deepen understanding of the 'language' of the genome, offering insights into human development. New research has uncovered more about the complexity of human gene ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...