The current research frontier in blastic plasmacytoid dendritic cell neoplasm (BPDCN) is moving toward combination triplet ...

Why do diabetic wounds refuse to heal? A new scientific review highlights how disruptions in the timing and behavior of ...

Potential autoimmune diseases therapies that target dendritic cells aim to either inhibit immunogenic dendritic cell functions or support their tolerogenic potential (Figure 2). Most strategies ...

Dendritic cells (DCs) are among the first immune sentinels to detect viruses, bacteria, or other challenges. These specialized messengers alert T cells while orchestrating either a measured calm or a ...

LMU researchers have shown that a particular type of immune cell acts more flexibly than previously thought - with potential for new therapeutic approaches. As part of the innate immune system, ...

Chronic diabetic ulcers represent one of the most challenging complications in modern healthcare, affecting over 131 million people worldwide and generating approximately $755 billion in annual ...

研究人员通过实验证实，当阻断树突状细胞的这条免疫通路后，幼年小鼠不再对过敏原产生皮肤炎症。更重要的是，这种早期干预还影响了远端的器官—那些原本在二次接触过敏原时会爆发剧烈肺部炎症的小鼠，症状明显减轻了。换句话说，皮肤或许是过敏战役的第一战场，但胜负可能在更早的时候就已注定。如果能在皮肤这个源头掐灭过敏的“火种”，或许就能阻止它蔓延到肺部（哮喘）、消化道（食物过敏）等其他器官。

A new study has revealed that a special group of cells in the intestines tamp down the immune responses caused by exposure to food proteins. Called 'tolerogenic dendritic cells,' these cells enable ...