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3 年
颅内注射B7-H3的CAR T疗法在恶性脑瘤中显示初步有效性与安全性
弥漫性内生性脑桥脑胶质瘤(diffuse intrinsic pontine glioma,DIPG)是一种发生于脑干的致命恶性肿瘤。在美国大约每年有300名儿童确诊,中位确诊年龄为6岁。约有85%的DIPG因为有组蛋白H3的K27M基因突变,被重新归类为弥漫性中线胶质瘤(diffuse midline glioma,DMG),但 ...
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