在治疗多发性硬化症（multiple sclerosis, RMS）时，淋巴细胞减少（lymphopenia）是富马酸（fumaric acids）的已知副作用。关于更换富马酸制剂对淋巴细胞计数影响的科学研究很少。本研究的目的是探讨从二甲基富马酸（dimethyl fumarate, DMF）转换为单甲基富马酸（monomethyl ...

为破解DMF高发的GI-AEs致停药难题，葡萄牙团队开展TMF 348 mg bid对比DMF 240 mg bid的5周随机双盲试验，结果显示TMF显著降低腹泻等事件发生率、持续时间和严重度，且零例因GI事件停药，提示TMF或成更具耐受性的RRMS一线口服DMT。 研究背景 多发性硬化（multiple sclerosis ...

The investigational drug diroximel fumarate (Vumerity, Biogen/Alkermes) showed statistically superior gastrointestinal (GI) tolerability compared with dimethyl fumarate (Tecfidera, Biogen) in patients ...

In a recent study posted to the medRxiv* preprint server, researchers evaluated the efficacy of the anti-inflammatory drug dimethyl fumarate (DMF) in treating coronavirus disease 2019 (COVID-19) as ...

HIGH POINT, N.C.--(BUSINESS WIRE)--Banner Life Sciences LLC (Banner), a privately held specialty pharmaceutical company, today announced that BAFIERTAM™ (monomethyl fumarate), a novel fumarate for ...

Immunological targeting of CD133 in recurrent glioblastoma: A multi-center phase I translational and clinical study of autologous CD133 dendritic cell immunotherapy. This is an ASCO Meeting Abstract ...

Credit: Getty Images. Treatment with diroximel fumarate was associated with significantly fewer days of key gastrointestinal symptoms, according to topline results from a phase 3 study evaluating the ...

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Please provide your email address to receive an email when new articles are posted on . Dimethyl fumarate was safe and lowered relapse rates for up to 5 years in Black and Hispanic/Latino patients ...

Please provide your email address to receive an email when new articles are posted on . BOSTON — Women with MS who were exposed to dimethyl fumarate in the first trimester had no unexpected adverse ...