Surface plasmon resonance (SPR) detectors monitor molecular interactions without labels and in real time. SPR imaging (SPRi) has the additional advantage of increased throughput since it monitors ...

Congestive heart failure is a disease state distinguished by the regular presence of both renal and hepatic abnormalities in drug handling. One such abnormality involves flaws in the process of drug ...

In this interview, News Medical talks to Patrick D. Sinko about the role of particle size, dose, and confinement parameters in advancing drug absorption modeling. Could you explain what a boundary ...

Passive diffusion plays an essential role in oral absorption of drugs through the gastrointestinal tract, penetration across the blood-brain barrier to reach Central Nervous System disease targets, ...

Though studies evaluating the effects of posture on the absorption of drugs have been conducted, a systematized review revealed critical gaps in methodology. Of 18 original research articles selected ...

Before orally administered drugs can make their way throughout the body, they must first bind to membrane proteins called drug transporters, which carry compounds across the intestinal tract and help ...