New electrophilic reagents for activity-based protein profiling (ABPP) can discriminate between nucleophilic amino acids, such as cysteine, that are in different protein microenvironments. These ...

Radiochemists can now expand their toolbox of molecular probes for positron emission tomography (PET), thanks to a new electrophilic fluorinating reagent. The palladium-based compound is made with 18 ...

In 2014, the European Medicines Agency approved the drug Tecfidera for the treatment of relapsing multiple sclerosis, a neurodegenerative disease that affects millions of people worldwide. In multiple ...