本期推荐一项神经眼科领域里程碑式研究：为解决特发性颅内高压（IIH）患者颅内压（ICP）控制难题，研究人员开展了一项前瞻性双盲随机对照试验。结果显示，GLP-1RA（exenatide）能在2.5小时内快速降低ICP，且效果独立于体重变化，为IIH治疗提供了新靶点。

本研究针对糖尿病引发的心力衰竭（HF）这一重大临床难题，探索了非甾体盐皮质激素受体拮抗剂Finerenone与胰高血糖素样肽-1 ...

Even with treatment, such as combined metformin and sulfonylurea, glycemic control can be compromised in patients with type 2 diabetes. Furthermore, these drugs are associated with weight gain. There ...

Male Harlan-Sprague-Dawley rats were treated with high-fat diet/streptozotocin to induce type 2 diabetes. After subcutaneous administration of a single dose of exenatide (4.2, 42, or 210 μg/kg), serum ...

Since May 2007, a new drug has been available for the treatment of patients with diabetes mellitus type 2 in Germany: exenatide (trade name: Byetta®), which is marketed by the manufacturer Eli Lilly.

In DURATION-1, Drucker et al sought to compare a long-acting-release formulation of exenatide (2 mg, injected once weekly) with 10-µg exenatide injected twice per day in 295 patients with type 2 ...

In combination with diet and exercise, the diabetes drug exenatide helped nondiabetic, obese individuals lose over three times more weight than those receiving a placebo, or dummy treatment, for 6 ...

The 121-patient, phase 2 study assessed the efficacy, safety and tolerability of three different doses of exenatide once monthly. It also assessed exenatide once weekly (exenatide extended-release for ...

One thing that all sides agree on in the tripartite fight over control of Amylin's board of directors is that the launch of exenatide once weekly, the long-acting version of its diabetes drug Byetta, ...

New Orleans, LA - Once-weekly treatment with the investigational agent exenatide (Byetta, Amylin Pharmaceuticals) resulted in better glycemic control than either daily sitagliptin (Januvia, Merck) or ...

The 121-patient, phase 2 study assessed the efficacy, safety and tolerability of three different doses of exenatide once monthly. It also assessed exenatide once weekly (exenatide extended-release for ...

Please provide your email address to receive an email when new articles are posted on . Umpierrez and colleagues conducted a multicenter, prospective, open-label, randomized trial with 150 adults who ...