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2月
BAF-1-VRK-1介导的减数分裂染色体从核 periphery释放对基因组完整性的 ...
本研究揭示了在秀丽隐杆线虫减数分裂早期,VRK-1激酶通过磷酸化BAF-1介导染色体从核 periphery释放的新机制。研究人员发现,干扰此过程会导致染色体配对延迟、联会异常、卵母细胞染色体畸变及凋亡增加。长读长测序显示VRK-1缺失后代中出现大量缺失和重复变异 ...
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