This article and associated images are based on a poster originally authored by Molly Jackson, Meng S. Choy, Wolfgang Peti and Suzanne Purseglove and presented at ELRIG Drug Discovery 2025 in ...
Researchers at BellBrook Labs have developed a high throughput screening (HTS) assay to discover small molecule modulators for the immunosuppressive ectonucleotidase, CD73. The Transcreener ADO CD73 ...
Immunoassay technology has advanced considerably since the era when all assays were performed in glass test tubes with dangerous radioactive tracers over a period of several days. The microtiter plate ...
The central role of protein kinases in signal transduction and recent clinical success with small molecule kinase inhibitor drugs, most notably Gleevec (Novartis), have generated intense interest in ...
The Transcreener ® ADPR Assay is a biochemical HTS test that quantitatively measures the production of ADP-ribose (ADPR) in enzymatic processes. The assay employs a coupling enzyme to transform ADPR ...