Luminescence and fluorescence-based assay methods prevail in modern HTS. Although invaluable as technologies, the problem of compound-related assay interferences such as quenching, auto-fluorescence, ...

Integrating Digital Holographic Microscopy with fluorescence techniques enhances live-cell imaging, preserving cellular ...

Biotium, a leading developer of fluorescent reagents for life science research, announces the launch of the RNaseReveal™ Activity Assay Kit, with unparalleled sensitivity to detect RNase contamination ...

Fluorescent dyes are tools used throughout biotechnology and medicine that offer a unique method of detecting and quantifying the presence of a target molecule, cell, or tissue within an even more ...

Learn best practices for HTS assay development, including validation, robustness, and Z-prime optimization for reliable ...

Modern bioassays tend to fall under three common modalities: colorimetric, luminometric or fluorometric. Colorimetric assays record the amount of light absorbed by a reporter compound. This absorbance ...

This article traces the history of high-throughput screening (HTS), describes key technological milestones, and examines the ...

The DeNovix™ DS-11 Series Spectrophotometer / Fluorometer facilitates precise absorbance and fluorescence quantification over an extensive dynamic range. The dual-mode spectrophotometer features ...

Novel Immunoassay Platform for Evaluating Multiple Analytes with Minimal Sample Volume The quantitative analysis of cytokines and other analytes in plasma, serum, or cell lysate is becoming ...