Sometimes, in genetics, two wrongs do make a right. A research team has recently shown that two harmful genetic variants, when occurring together in a gene, can restore function—proving a decades-old ...

When two defective gene variants combine, normal protein function can sometimes be restored.

Gene-set analysis seeks to identify the biological mechanisms underlying groups of genes with shared functions. Large language models (LLMs) have shown promise in generating functional descriptions ...

Sometimes, in genetics, two wrongs do make a right. A research team recently showed that two harmful genetic variants, when occurring together in a gene, can restore function—proving a decades-old ...

AlphaGenome is a DNA sequence model that advances regulatory variant-effect prediction to understand genome function.

Could a gene regulatory network in gut microbes have evolved its elaborate and tightly regulated molecular machinery only to pump out antibiotics indiscriminately? Researchers from the Institute of ...

IPA, a non-coding RNA from the CUL1 gene that stabilizes the nucleolus and supports ribosome production. Removing it ...

The DGIST Center for Synapse Diversity and Specificity has identified MDGA2 as a novel causative gene for developmental and ...

Early in development, many animals pick a team—male or female—based on their genetics, and, with time, acquire the ...

A duplicated gene evolved into a switch that determines sex in frogs, revealing how evolution can safely reshape critical ...