In 1869, Swiss scientist Friedrich Miescher isolated a mysterious substance from cell nuclei—an overlooked finding that would ...

Gene regulation and chromatin dynamics constitute central themes in modern molecular biology, governing how the genetic blueprint is accessed and utilised during development, differentiation and ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

Researchers showed how what appears to be a tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published as two papers in Nature ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Until now, scientists had believed that ...

DNA might be too small to see with the unaided eye, but it packs our cells in shocking quantities: More than six and a half feet of DNA lies within every cellular nucleus. It squeezes into such a ...

DNA’s iconic double helix does more than “just” store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., at UMass Chan Medical School, has extensively mapped and analyzed the three ...