这篇综述深入探讨了（Genotoxicity）基因毒性物质对生物体遗传物质的损伤机制，系统梳理了高通量筛选技术（HTS）和基因组学方法在DNA损伤修复研究中的应用，为疾病预防诊断提供了新思路。 ABSTRACT 基因毒性（Genotoxicity）是指有害物质对生物体遗传物质造成的 ...

In a recent study published in Addiction Biology, authors explored the mechanisms of cannabinoid-induced mitochondrial stress, micronuclear formation, and genotoxic damage and their implications for ...

在遗传毒性评估中，QSAR 模型应用广泛，但 OECD QSAR Toolbox 分析器的可靠性存疑。研究人员用 MultiCASE 数据库数据验证其准确性，发现无警报与实验阴性结果相关性好，纳入代谢模拟可提高准确性。该研究为遗传毒性评估提供参考。 在化学物质的安全评估流程里 ...

Scientific research in areas such as drug development and the food industry requires rigorous testing of new chemical compounds to determine their safety for the open market and human use. One vital ...

With industry spinning that glyphosate is harmful to health, if at all, only with co-formulants like tallowamine, the World Health Organisation's cancer agency IARC has just released a Q&A document ...

SAN FRANCISCO and TORONTO, April 01, 2021 (GLOBE NEWSWIRE) -- Claritas Pharmaceuticals, Inc. (formerly Kalytera Therapeutics, Inc.) (TSX VENTURE: KLY and OTC: KALTF) (the "Company" or "Claritas") ...

A team of researchers from the Eichman lab and associated with the Evolutionary Studies Initiative led a project that was recently published in mBio. Graduate student Noah Bradley and undergraduate ...