A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune response in five preclinical models of head and neck cancer, according to ...

Co-corresponding authors Jian Xu,PhD, (left) and Min Ni, PhD, (right) and co-first authors Junhua Lyu, PhD, (center left) and Yuannyu Zhang, PhD, (center right) identified and characterized a ...

New research has discovered that a fundamental nutrient found in cells is key to maintaining the body’s cancer-destroying immune response. The discovery may lead to more effective ways of treating the ...

L-glutamine is a semi-essential amino acid that the body produces on its own, but in situations of exertion, stress, or ...

The amino acid glutamine plays an unexpected role in erythropoiesis, the differentiation of erythroid progenitor cells into mature red blood cells. Ordinarily, glutamine is broken down by stem cells ...

A mitochondrial glutamine transporter variant is a key regulator of glutamine metabolism and metabolic reprogramming in cancer cells, and targeting such transporters could be a new strategy for ...

While most people are familiar with the need for vitamins and minerals in a balanced diet, there are certain nutrients that are often overlooked—glutamine being one of them. Glutamine is an amino acid ...

BATF2 is a new type of tumor suppressor that can be epigenetically silenced by high levels of glutamine in the tumor microenvironment Glutamine silences BATF2 and leads to a weakened immune response ...