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Gram-negative bacteria deploy a range of protein toxins as mediators of inter-bacterial competition and pathogenicity. Among these, colicins comprise a class of ribosomally synthesised bacteriocins ...

Antimicrobial resistance has become one of the greatest threats to public health, with rising resistance to carbapenems being a particular concern due to the lack of effective and safe alternative ...

The Tol-Pal complex maintains bacterial outer membrane (OM) stability by regulating lipid homeostasis. (Left) In Gram-negative bacteria, the OM acts as a protective barrier, blocking entry of harmful ...

Lead clinical candidate CTX-187 is a novel antimicrobial immunotherapy developed to treat clinically-prevalent and multi-drug resistant Gram-negative bacterial infections -- Qualified Infectious ...

Gram-negative meningitis is a form of meningitis. The term gram-negative refers to a way of differentiating bacteria. This type of bacteria is typically resistant to drugs and most available ...

Expert Rev Anti Infect Ther. 2010;8(8):879-885. We recommend a thorough evaluation of patients with non-HACEK Gram-negative endocarditis to assess the necessity of surgical intervention. Decision to ...

Scientists at Duke University report they have developed a synthetic antibiotic that could be effective against drug-resistant superbugs and bacteria such as Salmonella, Pseudomonas, and E. coli.

Animals house thousands of commensal bacterial species in their guts, which play an important role in maintaining the host’s health. 1 However, antibiotic treatment indiscriminately wipes out both ...