The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Although there are more than 150 guanosine triphosphate (GTP)–binding proteins, or GTPases, only the GTPase KRas G12C has proved susceptible to small-molecule drugs. That’s because it’s tough to find ...

Guanosine, a purine nucleoside, has emerged as a potent modulator within the central nervous system (CNS), contributing to neuroprotection through a diverse array of mechanisms. It plays a critical ...

In a recent study published in the Developmental Cell Journal, researchers reported that reproductive aging in Caenorhabditis elegans is regulated through an interaction of the metabolism of ...

Adenosine triphosphate (ATP) is a molecule that provides crucial energy to activate a wide array of biological processes, in many organisms including the movement of muscles and the propagation of ...

In a paper published recently in the journal GeroScience, the UC Irvine team reports that a combination of naturally occurring compounds – nicotinamide (a form of vitamin B3) and epigallocatechin ...