Nature

Acid-Cleavable Guanosine Triphosphate-Photoaffinity Probe for Global Profiling of Guanosine Triphosphate-Binding Proteins and Their Active Sites

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...
C&EN

Drugging more enzymes in KRas’s family

Although there are more than 150 guanosine triphosphate (GTP)–binding proteins, or GTPases, only the GTPase KRas G12C has proved susceptible to small-molecule drugs. That’s because it’s tough to find ...
Labroots

ATP & GTP Are Common in Biology - But What About CTP?

Adenosine triphosphate (ATP) is a molecule that provides crucial energy to activate a wide array of biological processes, in many organisms including the movement of muscles and the propagation of ...
Nature

Developing inhibitors of the guanosine triphosphate hydrolysis accelerating activity of Regulator of G protein Signaling-14

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...
News Medical

Mitochondrial GTP metabolism acts through mitochondrial dynamics factors to regulate reproductive aging

In a recent study published in the Developmental Cell Journal, researchers reported that reproductive aging in Caenorhabditis elegans is regulated through an interaction of the metabolism of ...