Researchers have identified a suite of genes and regulatory elements critical to normal heart development. Their study outlines the importance of 'hub genes' in heart development. The advent of genome ...

A recent Nature study uses a combination of single-cell ribonucleic acid (scRNA)-sequencing and high-resolution multiplexed error-robust fluorescence in situ hybridization (MERFISH) to better ...

Scientists at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences have developed a multi-chamber organoid that mirrors the heart’s intricate structure. The human ...

In humans, a specialized mRNA translation circuit predetermines the competence for heart formation at an early stage of embryonic development, a research team at the Center for Molecular Medicine ...

Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists – so far. A new multi-chamber organoid ...

The most comprehensive cell "atlas" of the developing human heart to date was crafted using cutting-edge technology and includes never-before-seen cell types. When you purchase through links on our ...

Having explored how the heart is formed in utero, a researcher is reporting how cells and molecules act during that early formation and what might cause the heart disease called left ventricular ...

A crucial new mechanism that helps explain how the heart’s major blood vessels form during early development – and how disruptions to this process can lead to serious congenital heart defects – has ...

A lab in Vienna has used stem cells to create thousands of tiny heart-like structures. Each miniature heart, dubbed a “cardioid,” is the size of a sesame-seed and has a hollow chamber that beats.