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综述:MALDI-TOF MS在病原体直接快速鉴定中的临床应用:一项聚焦于血 ...
直接MALDI-TOF MS快速鉴定病原体在血液等无菌体液中的应用研究,发现其可在30-60分钟内完成病原体鉴定,但存在革兰氏阴性菌识别率高于阳性菌及真菌的现象,主要受样本中微生物浓度、细胞壁结构及蛋白质提取效率影响,同时面临低灵敏度样本、基质干扰、多 ...
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