The Epstein-Barr virus and a high-risk gene may work together to trick the immune system into attacking the brain in MS, a ...

How can TCR-based therapeutics address the current limitations of treating solid tumors? The TCR increases the number and types of proteins available to surveilling T cells. Unlike a CAR, which only ...

Patients with celiac disease have gluten-specific CD4+ T cells that recognize gluten via disease-associated human leukocyte antigen (HLA) molecules, specifically HLA-DQ2.5, leading to immune ...

How does the immune system fight cancer? In smokers, having diverse HLA-II genes helps by presenting tobacco-related antigens, aiding in early cancer detection. Thus, genetic variation in ...

“Since the discovery of transplantation as a life-saving therapy for blood malignancies by Dr. E Donnall Thomas, there have been major advances that have significantly lowered the side effects and ...

Researchers at the University of Oslo and Oslo University Hospital have developed a promising new immunotherapy targeting the CTNNB1 gene mutation associated with various aggressive cancers like lung ...