Conjugated hyperbilirubinemia occurs when bilirubin, a by-product of red blood cells, builds up in the blood. This can indicate several underlying causes, such as hepatitis, cirrhosis, or biliary ...

Bilirubin, the primary breakdown product of hemoproteins, particularly hemoglobin, plays a key role in the diagnosis, prognosis, and monitoring of liver diseases. In acute liver diseases, such as ...

Crigler-Najjar syndrome (CNS) and Gilbert syndrome (GS) are rare autosomal recessive disorders causing unconjugated hyperbilirubinemia due to reduced UGT1A1 enzyme activity, with CNS type 2 (CNS2) ...

Dubin-Johnson syndrome is a genetic condition that prevents the liver from properly removing bilirubin, leading to a harmless but permanent yellowing of the skin and eyes. The syndrome results from ...

Did our AI summary help? One of the most common conditions that is observed in newborns within the first week of life is neonatal jaundice. It presents as a yellowish discolouration of the skin and ...