Interleukin-6 (IL-6) is a multifaceted cytokine that serves as a critical mediator in immune regulation, inflammation and tissue regeneration. Its activity is mediated through several signalling ...

重组IL-1β蛋白（Interleukin-1β，白介素-1β，AbMole，M21094）是一种通过基因工程表达的重要促炎细胞因子，在免疫调控和炎症研究中具有核心作用。IL-1β通过结合IL-1RI（I型IL-1受体）并招募辅助蛋白IL-1RAcP，激活NF-κB信号通路，进而调控下游炎症因子的释放[1]。IL-1β常用于模拟细胞的炎症反应，例如在RAW2 ...

Interleukin (IL)-1 is a prototypic proinflammatory cytokine. It is produced by numerous cell types (i.e., macrophages, synoviocytes, endothelial cells, chondrocytes, osteoclasts) and is found in ...

Monoclonal antibodies targeting IgE, interleukin-4 and -13, and interleukin-5 are effective in treating severe type 2 asthma, but new targets are needed. Itepekimab is a new monoclonal antibody ...

Interleukin-6 (IL-6) is a pleiotropic cytokine that may play a role in the regulation of various aspects of the immune response, inflammation, hematopoiesis, and bone metabolism. IL-6 acts by binding ...

Dupilumab (interleukin-4Rα; antibody binds to interleukin-4Rα, inhibiting interleukin-4 and interleukin-13 signaling in hematopoietic cells [e.g., B cells, CD4+ helper T cells, and eosinophils], ...