宿主包虫囊蚴分泌的抗原B(EgAgB)是一种脂蛋白,可显著抑制脂多糖(LPS)诱导的骨髓来源树突状细胞(BMDC)炎症反应,其机制包括EgAgB与LPS结合,干扰TLR4信号通路中的二聚化和内吞作用,同时EgAgB自身可轻微激活BMDC。动态光散射和ELISA-like实验证实EgAgB8/1亚基 ...
急性肺损伤(ALI)的研究:Naftidrofuryl通过调节NLRP3/TLR4通路改善LPS诱导的ALI。体外实验显示,LPS可激活巨噬细胞并改变CD11b ...
早期自然流产(ESA)被定义为妊娠12周前的非意愿妊娠终止,全球发生率约10%,且随年龄、免疫及内分泌异常而攀升。传统西医以补充孕酮、抗凝、免疫调节为主,但循证证据有限,复发风险仍高。
The research was led by Prof. Fuping Zhang from the Institute of Microbiology, Chinese Academy of Sciences, in collaboration with Prof. Jian Song from the Guangxi Zhuang Autonomous Region People's ...
Scientists reveal that the structure of gut bacteria-derived LPS determines whether cancer immunotherapy succeeds or fails—unlocking a new path to personalized treatments. Analysis: Gut ...