Lipoprotein lipase (LPL) hydrolyzes circulating triglycerides (TGs). We previously showed that 3′-end haplotypes in the LPL gene influence atherosclerosis and insulin resistance. This study asked ...

Activity was measured by the amount of free fatty acids released by control or postheparin plasma from an artificial lipoprotein triglyceride substrate during one hour of incubation at 37°C. as ...

Purpose: Our aim was to test whether polymorphisms in the lipoprotein lipase (LPL) gene were associated with the progression of atherosclerosis in grafts examined in the Post-Coronary Artery Bypass ...

During the first 18 months after treatment with ali-pogene tiparvovec, a gene therapy recently approved in Europe to treat lipoprotein lipase deficiency (LPLD), the first patient to receive the ...

Although able to hydrolyze a coconut-oil emulsion, the postheparin plasma of a patient with fat-induced (Type 5) hyperlipemia was unable to hydrolyze his own, normal human or rat chylomicrons.

Familial hyperchylomicronemia syndrome (FCS) is a rare disorder you get from genes passed down from your parents. When you have it, your body isn’t able to break down (metabolize) fat. Specifically, ...

Over a 6-year period, patients with the genetic disease lipoprotein lipase deficiency (LPLD) who received a single gene therapy treatment of alipogene tiparvovec had a marked reduction in the severity ...

New Rochelle, NY, May 1, 2018--During the first 18 months after treatment with ali-pogene tiparvovec, a gene therapy recently approved in Europe to treat lipoprotein lipase deficiency (LPLD), the ...