Lithium may cause anterograde amnesia, slightly slowed motor movement, and diminished creativity; however, those symptoms could be associated with bipolar disorder itself as opposed to lithium use.
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Can Lithium Protect the Aging Brain?

Glimmer of hope emerges in pilot trial of people with mild cognitive impairment ...
A once-daily dose of a medication, which averaged 195 mg, produced blood levels significantly lower than those typically pursued by psychiatrists. However, it succeeded in generating a weak signal ...
A study published in Nature on August 6, 2025, found that lithium is the only metal significantly depleted in the prefrontal ...
An exploratory clinical trial from the University of Pittsburgh has found that low-dose oral lithium may help slow the decline of verbal memory in older adults with mild cognitive impairment.