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MIT开发Pichia-CLM模型学习酵母DNA「语言」,外源蛋白产量最高可提高至3倍
作者:梅菜编辑:李宝珠转载请联系本公众号获得授权,并标明来源来自麻省理工学院的研究团队提出一种基于深度学习的语言模型 Pichia-CLM,用于在工业相关宿主毕赤酵母中进行密码子优化,以提升重组蛋白的产量。研究人员在 6 类不同复杂度的蛋白上对 Pichia-CLM 进行了实验验证,并且与 4 ...
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