来自澳大利亚彼得-麦卡伦癌症中心等机构的科学家们通过利用黑腹果蝇(Drosophila melanogaster)作为研究癌症恶病质的模型，结果发现，肿瘤会分泌一种名为Mmp1的酶类，该酶主要负责分解脂肪和肌肉。 2021年9月4日 讯 /生物谷BIOON/ --恶病质（Cachexia）是一种肿瘤诱发 ...

本研究针对非小细胞肺癌(NSCLC)高转移特性导致的临床治疗困境，通过体内外实验首次揭示溶瘤疱疹病毒OH2通过其皮层蛋白UL41 ...

Matrix metalloproteinases (MMPs) have a key role in the invasion and metastasis of a variety of tumors. Researchers have investigated whether epithelial (tumor-cell-derived) and stromal (host-derived) ...

推荐 为解决肥胖加速乳腺癌转移的问题，南京医科大学研究人员开展研究。结果表明，NRG4作为关键调节因子，通过ERBB4 - YAP1信号轴抑制MMPs转录，进而抑制乳腺癌细胞迁移和转移。这为靶向NRG4 - ERBB4信号治疗肥胖驱动的乳腺癌提供了理论依据。 论文解读 乳腺癌 ...

Find a way to control cell movement, and you've got an excellent weapon in the fights against tumorigenesis and inflammation, an excellent clue as to how organisms develop, and an excellent tool in ...

Matrix metalloproteinases (MMPs), a family of zinc-dependent endopeptidases, are capable of degrading almost all protein components of the extracellular matrix (ECM). MMPs have garnered attention as ...

日前，华大生命科学研究院联合多家机构发布了一项自主研发的基于并行原理的DNA合成技术——mMPS技术。该技术以微芯片的创新范式，从源头颠覆了DNA合成技术，成功在合成通量、产量和质量方面实现了系统性突破，有望为基因组编写、疫苗快速开发与DNA数据 ...

Lymphangioleiomyomatosis, a rare lung disease typically affecting women of reproductive age, is characterized by an abnormal proliferation of smooth-muscle cells and the progressive loss of pulmonary ...