本研究探讨了MTNR1B基因多态性(rs1387153、rs10830963等)与妊娠期糖尿病(GDM)风险的关联,发现rs1387153_T和rs10830963_G等位基因 ...
这篇研究通过CRISPR/Cas9基因编辑技术,在携带MTNR1B rs10830963风险变异(G等位基因)的2型糖尿病(T2D)患者诱导多能干细胞 ...
Genome-wide association studies have shown that variation in MTNR1B (melatonin receptor 1B) is associated with insulin and glucose concentrations. Here we show that the risk genotype of this SNP ...
Eating dinner close to bedtime, when melatonin levels are high, disturbs blood sugar control, especially in individuals with a genetic variant in the melatonin receptor MTNR1B, which has been linked ...
A sleeping pancreas releases less insulin, but how much insulin drops each night may differ from person to person, suggests a study published May 12, 2016 in Cell Metabolism. Up to 30 percent of the ...
Taking melatonin close to mealtimes may put people with the genetic variant MTNR1B at a greater risk for developing type 2 diabetes, according to recent study findings published in Metabolism. “Our ...
December 8, 2008 — Variants in MTNR1B, a gene that codes for human melatonin receptor MT2, are associated with fasting glucose levels and risk for type 2 diabetes, according to 3 studies appearing ...