BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

Schematic of UV-W process. (a) Schematic of UV-W process. (b) Positron annihilation lifetime spectroscopy of the PEI-IIM, PEI-ICM with UV-W process 20 h and 40 h. (c) Ion permeation and selectivity ...

This is an important study on the sensory roles of Cerebrospinal fluid-contacting neurons (CBF-cn) in mammals. The authors identify PKD2L1 as the predominant pH-sensing channel CBF-cn and show how the ...

Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.