The mitochondria, perhaps better known as the powerhouses of cells, are emerging as a possible factor in the pains of aging.

Patients with rare mitochondrial diseases already face a host of serious health issues, from muscle weakness to neurological problems and heart conditions. But one of their most life-threatening ...

Mitochondrial DNA has long been treated as a workhorse record of cellular history, but new research suggests it also hides a subtle and previously overlooked form of damage. By uncovering this cryptic ...

Researchers from the Mitochondrial Medicine Program at Children's Hospital of Philadelphia (CHOP) have better characterized a spectrum of what were classically considered discrete mitochondrial DNA ...

For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these mutations cause serious diseases that pass down only through mothers. They ...

Researchers uncover how cells internalize transplanted mitochondria, paving the way for new energy-restoring therapies for Parkinson’s and Alzheimer’s.

Millions of people worldwide live with mitochondrial diseases. These are inherited conditions that make it hard for the body’s cells to produce energy. For a long time, patients had few options ...

Andrew Joseph covers health, medicine, and the biopharma industry in Europe. You can reach Andrew on Signal at drewqjoseph.71. Megan Molteni reports on discoveries from the frontiers of genomic ...

Pretzel Therapeutics, a leader in harnessing cellular energetics to develop novel treatments for a range of conditions spanning neurological, muscle, metabolic and rare diseases, today announced the ...