During restricted periods of development (embryonic day (E) 14.5-E15.5 in mice 1), peripheral innervation of a subset of type I myotubes by group Ia sensory (but not motor 9) axons provides ...

IN the past 30 years many experiments have been carried out on the structure and function of muscle spindles in both amphibia and mammals. There have been no accounts of experiments concerned with the ...

After complete transection of a nerve, good neuroanastomosis is needed to prevent the formation of fibrous connective tissues that form obstacles to nerve regeneration, and to facilitate repair of the ...

Knowing where our bodies are in space is critical for the control of our movements and for our sense of self. Feedback from muscle spindles and tendon organs provides information about where our ...

Scattered throughout skeletal muscle, the muscle spindles are composed of connective tissue capsules containing bundles of specialized muscle fibers called intrafusal fibers. Wrapped around the middle ...

Scientists have discovered yet another function for β-secretase (BACE1), the enzyme that kick-starts amyloidogenic processing of the amyloid-β precursor protein. In the June 21 EMBO Journal, ...

A new study from Umeå University, Sweden, shows that the body's muscles sense mechanical pressure. This new discovery has important implications for movement neuroscience and may improve the design of ...