异位骨化术后预防效果及选择性非甾体抗炎药比较:系统综述和元分析显示,选择性(塞来昔布)和非选择性(吲哚美辛、布洛芬)NSAIDs在降低肘部创伤术后异位骨化发生率方面均未达到统计学显著差异,但整体分析显示NSAIDs组较对照组风险降低27%。研究强调需 ...
BAE: Bovine aortic endothelial; RHP: Recombinant human protein. NSAIDs variably inhibit prostaglandin H synthase (COX). COX-2 was cloned in 1991, and it was subsequently established that COX-1 does ...
Aspirin was introduced into clinical medicine in 1899 and its anti-inflammatory, analgesic and antipyretic properties were accompanied by the onset of gastrointestinal and renal toxicity. Over the ...
The discovery of cyclooxygenase (COX) isoforms, COX-1 and COX-2, in the early 1990s helped explain how non-steroidal anti-inflammatory drugs (NSAIDs) work and led to specific agents with fewer ...
CONCORD, Mass.--(BUSINESS WIRE)--Tremeau Pharmaceuticals today announced that it will host a key opinion leader (KOL) webinar to discuss the unmet medical need in migraine management and the potential ...
NEW YORK (Reuters Health) - Although all of the common strategies protect the upper gastrointestinal tract from the complications of nonsteroidal anti-inflammatory drugs (NSAIDs), popular ...
Ibuprofen’s anti-inflammatory action may influence cancer risk, but evidence remains complex and routine use for prevention is not advised. Ibuprofen is one of the most widely used pain relievers, ...
Non-steroidal anti-inflammatory drugs (NSAIDs) and steroids (see Corticosteroid Therapy) can be useful for acute pain relief in patients with rheumatoid arthritis (RA). In osteoarthritis, studies have ...