Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis system. Archaeosine is a modified nucleoside found only in the tRNAs from archaea, the so-called third ...

To understand more fully the role of RNA and its modifications in living systems, researchers will need robust, reproducible, and accessible tools and techniques capable of identifying all RNA ...

Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...

A single enzyme that can generate all four nucleoside triphosphates, the building blocks of ribonucleic acid (RNA), has been identified by researchers at the Institute of Science Tokyo. The study was ...

It’s early October—the time of year when a few, select, researchers receive an early morning phone call from Stockholm. The first of the Nobel prizes awarded, announced on Monday morning, was the ...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and the resulting disease, coronavirus disease 2019 (Covid-19), have spread to millions of persons worldwide. Multiple vaccine ...

Researchers found that the relative efficacy of the modRNA vaccine was 34.5% against influenza-like illness compared with the control vaccine, on the basis of 57 and 87 cases in the modRNA and control ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

A vascular dilatation in the aorta can be life-threatening if it bursts. These so-called aortic aneurysms typically form in the same sites of the large blood vessel: either on the upper arch or in the ...

Suggested Citation: "1 Introduction." National Academies of Sciences, Engineering, and Medicine. 2024. Charting a Future for Sequencing RNA and Its Modifications: A New Era for Biology and Medicine.